Monoclonal Anti-Cytokeratin Peptide 7

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1024

Size

100ug/vial

Applications

IHC, IHC-Fr, WB

Reactivities

Hum

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(3855), Mouse(110310), Rat(300242)

Swiss Prot

Human(P08729), Mouse(Q9DCV7), Rat(Q6IG12)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

SCL; cytokeratin 7; K2C7; K7; keratin; Keratin-7; 55K type II cytoskeletal; keratin, type II cytoskeletal 7; sarcolectin; ; KERATIN, SIMPLE EPITHELIAL; KERATIN, TYPE II, CYTOSKELETAL, 7; SARCOLECTIN; Type-II keratin Kb7

Primary Protein

Keratin, type II cytoskeletal 7

Scientific Background

KRT7 is a type II keratin of simple nonkeratinizing epithelia. The deduced 489-amino acid protein has a calculated molecular mass of about 54 kD. K7 contains 4 central alpha-helical segments with heptad repeats of hydrophobic residues characteristic of a coiled-coil region. Within this domain, K7 shares 73% homology with epidermal K6B. KRT7 gene contains 9 exons and spans more than 15.6 kb. K7 gene is mapped to chromosome 12. Keratin 7 is expressed in a wide range of epithelial structures in humans.