Monoclonal Anti-Cyclin D1

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1033

Size

100ug/vial

Applications

ICC, IHC, IHC-Fr, WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(595), Mouse(12443), Rat(58919)

Swiss Prot

Human(P24385), Mouse(P25322), Rat(P39948)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

BCL1; U21B31; D11S287; PRAD1; B-CELL LEUKEMIA 1; B-cell CLL/lymphoma 1; G1/S-specific cyclin D1; parathyroid adenomatosis 1; B-cell lymphoma 1 protein\n; BCL-1 oncogene; PRAD1 oncogene

Primary Protein

G1/S-specific cyclin-D1

Scientific Background

D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.