Monoclonal Anti-Collagen, Type ?

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1030

Size

100ug/vial

Applications

IHC, IHC-Fr

Reactivities

Hum

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(1282), Mouse(12826), Rat(290905), Human(1285), Mouse(12828), Rat(363256), Human(1286), Mouse(12829), Rat(301562), Human(1287), Mouse(12830), Rat(363457), Human(1288), Mouse(94216)

Swiss Prot

Human(P02462), Mouse(P02463), Rat(Q5FWY9), Human(Q01955), Mouse(Q9QZS0), Rat(F1LRJ1), Human(P53420), Mouse(Q9QZR9), Rat(Q5U1X9), Human(P29400), Mouse(Q63ZW6), Rat(F1LUN5), Human(Q14031), Mouse(B1AVK5)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

ICH; HANAC; POREN1; arresten

Primary Protein

Collagen alpha-1(?) chain; Collagen alpha-3(IV) chain; Collagen alpha-4(IV) chain; Collagen alpha-5(IV) chain; Collagen alpha-6(IV) chain

Scientific Background

Collagen IV is comprised of a third chain (alpha-3) together with the 2 classical ones, alpha-1 and alpha-2. COL4A3 gene is localized to 2q36-q37 by analysis of somatic cell hybrids and by in situ hybridization. The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria.