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Products Monoclonal Anti-CDK4
| Catalogue number: | MA1020 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat |
| Applications: | Immunocytochemistry, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(1019), Mouse(12567), Rat(94201) |
| Swiss prot: | Human(P11802), Mouse(P30285), Rat(P35462) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | PSK-J3; CELL DIVISION KINASE 4; Cell division protein kinase 4 |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Cyclin-dependent kinase 4 |
| Scientific background: | Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells. |
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