Monoclonal Anti-CDC25C

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1018

Size

100ug/vial

Applications

WB

Reactivities

Hum

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(995), Mouse(12532), Rat(307511)

Swiss Prot

Human(P30307), Mouse(P48967), Rat(D4ADT2)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

CDC25; PPP1R60; MITOSIS INDUCER CDC25; cell division cycle 25C; protein phosphatase 1, regulatory subunit 60; Dual specificity phosphatase Cdc25C

Primary Protein

M-phase inducer phosphatase 3

Scientific Background

Cell division sycle(CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34(cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53,000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31.