Catalogue number: |
MA1018 |
Price: |
$200.00 |
Reactivities: |
Human |
Applications: |
Western Blot |
Size: |
100ug/vial |
Gene: |
Human(995), Mouse(12532), Rat(307511) |
Swiss prot: |
Human(P30307), Mouse(P48967), Rat(D4ADT2) |
Form: |
Lyophilized |
Format: |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Target synonym: |
CDC25; PPP1R60; MITOSIS INDUCER CDC25; cell division cycle 25C; protein phosphatase 1, regulatory subunit 60; Dual specificity phosphatase Cdc25C |
Storage temp: |
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
Primary protein: |
M-phase inducer phosphatase 3 |
Scientific background: |
Cell division sycle(CDC25) gene product is a protein-tyrosine phosphatase, activates a partially purified p34(cdc2)/cyclin B complex. The cdc25 protein also shares homology with a protein phosphatase with activity against both tyrosine and serine (and thus probably threonine) phosphate residues. CDC25C is expressed predominantly in G2 phase in healer cells. The human gene encodes a protein with a predicted molecular mass of 53,000 daltons whose C-terminal domain shares about 37% sequence identity with the fission yeast cdc25 mitotic inducer. CDC25C gene is mapped to 5q31. |