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Products Monoclonal Anti-CD3
| Catalogue number: | MA1015 |
| Price: | $200.00 |
| Reactivities: | Human |
| Applications: | Immunohistochemistry - frozen |
| Size: | 100ug/vial |
| Gene: | Human(916), Mouse(12501), Rat(315609) |
| Swiss prot: | Human(P07766), Mouse(P22646), Rat(D4A5M2) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | T3E; T-cell surface antigen T3/Leu-4 epsilon chain; |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | T-cell surface glycoprotein CD3 epsilon chain |
| Scientific background: | The alpha-beta heterodimeric T-cell antigen receptor binds antigen in association with major histocompatibility complex proteins on host cell surfaces. These 2 disulfide-linked glycoproteins, TCRA and TCRB are associated on T-cell surfaces with a complex of proteins called CD3 (formerly T3). Human CD3 consists of at least 4 proteins: gamma, delta , epsilon, and zeta . The CD3-gamma/CD3-delta gene pair is within 300 kb of the CD3-epsilon gene and therefore these genes form a tightly linked cluster on 11q23. The clustering may be significant in terms of their simultaneous activations during T-cell development. |
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