Catalogue number: |
MA1005 |
Price: |
$200.00 |
Reactivities: |
Human, Mouse, Rat |
Applications: |
Immunocytochemistry, Immunohistochemistry - frozen, Western Blot |
Size: |
100ug/vial |
Gene: |
Human(274), Mouse(30948), Rat(117082) |
Swiss prot: |
Human(O00499), Mouse(O08539), Rat(O08839) |
Form: |
Lyophilized |
Format: |
1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Target synonym: |
AMPHL; AMPH2; SH3P9; amphiphysin II; Amphiphysin-like protein;Box-dependent myc-interacting protein 1;Bridging integrator 1 |
Storage temp: |
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
Primary protein: |
Myc box-dependent-interacting protein 1 |
Scientific background: |
BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei. |