Monoclonal Anti-BIN1

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1005

Size

100ug/vial

Applications

ICC, IHC-Fr, WB

Reactivities

Hum, Mouse, Rat

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(274), Mouse(30948), Rat(117082)

Swiss Prot

Human(O00499), Mouse(O08539), Rat(O08839)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

AMPHL; AMPH2; SH3P9; amphiphysin II; Amphiphysin-like protein;Box-dependent myc-interacting protein 1;Bridging integrator 1

Primary Protein

Myc box-dependent-interacting protein 1

Scientific Background

BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei.