Monoclonal Anti-alpha-Adaptin

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SPECIFICATIONS

Price

200.00 USD

Catalog Number

MA1105

Size

100ug/vial

Applications

WB

Reactivities

Hum, Rat

Form

Lyophilized

Format

1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Gene Id

Human(160), Mouse(11771), Rat(308578)

Swiss Prot

Human(O95782), Mouse(P17426), Rat(D3ZUY8)

Storage Temp

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Target Synonym

ADTAA; CLAPA1; AP2-ALPHA\n

Primary Protein

AP-2 complex subunit alpha-1

Scientific Background

Alpha Adaptin, also known as adaptor related protein complex, alpha 1 subunit. The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1 (HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. . Waelter et al. (2001) identified 3 HIP1-associated proteins, clathrin heavy chain (CLTC)and alpha-adaptin A and C. Coat proteins of approximately 100-kD (adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels.