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Products Monoclonal Anti-alpha-Adaptin
| Catalogue number: | MA1105 |
| Price: | $200.00 |
| Reactivities: | Human, Rat |
| Applications: | Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(160), Mouse(11771), Rat(308578) |
| Swiss prot: | Human(O95782), Mouse(P17426), Rat(D3ZUY8) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | ADTAA; CLAPA1; AP2-ALPHA |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | AP-2 complex subunit alpha-1 |
| Scientific background: | Alpha Adaptin, also known as adaptor related protein complex, alpha 1 subunit. The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1 (HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. . Waelter et al. (2001) identified 3 HIP1-associated proteins, clathrin heavy chain (CLTC)and alpha-adaptin A and C. Coat proteins of approximately 100-kD (adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels. |
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