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Products Monoclonal Anti-alpha-Actinin
| Catalogue number: | MA1104 |
| Price: | $200.00 |
| Reactivities: | Human, Mouse, Rat, Rabbit |
| Applications: | Immunohistochemistry, Immunohistochemistry - frozen, Western Blot |
| Size: | 100ug/vial |
| Gene: | Human(88), Mouse(11472), Rat(291245) |
| Swiss prot: | Human(P35609), Mouse(Q9JI91), Rat(D3ZCV0) |
| Form: | Lyophilized |
| Format: | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
| Target synonym: | CMD1AA; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein |
| Storage temp: | At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing. |
| Primary protein: | Alpha-actinin-2 |
| Scientific background: | Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin. |
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