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Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors...
Destrin belongs to the actin-binding proteins ADF/cofilin family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo....
DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase family. This member contains a nuclear targeting signal sequence, a...
EPH receptor A3 (ephrin type-A receptor 3) is a protein belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related...
The predicted human ERCC4 protein has 2 leucine zipper domains in the N-terminal region. ERCC4 protein expressed in mammalian cells has a molecular mass of...
Coagulation factor XII circulates in blood as a zymogen. This single chain zymogen is converted to a two chain serine protease with an heavy chain (alpha...
Fas is a glycoprotein with a mass estimated at 43 to 48 kDa . Fas is a member of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), and it shares a...
Fibrinogen gamma chain is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains....
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial...
Flot1 encodes a deduced 428-amino acid protein with a predicted molecular mass of 47 kD. It contains 2 hydrophobic domains and several potential...
FNDC5 contains an N-terminal signal peptide, a fibronectin type III domain, and a transmembrane domain. The 2 proteins share 60% identity in the FNIII domain...
Folate receptor beta is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have...
FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA binding domain. There are...
FSIP1, also known as HDS10, is a recently discovered gene that encodes fibrous sheath interacting protein 1, and is regulated by amyloid beta precursor...
Glucagon has a major role in maintaining normal concentrations of glucose in blood, and is often described as having the opposite effect of insulin. That is,...
Angiopoietin-2 (Ang-2) is a secreted glycoprotein that plays a complex role in vascular development. Ang-2 contains an N-terminal coiled-coildomain, 58 - 254...
Fetal hemoglobin is the main oxygen transport protein in the fetus during the last seven months of development in the uterus and in the newborn until roughly...
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains...
HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat...
The IFNA21 gene was positioned in the cluster of interferon genes on 9p22 by deletion mapping. Interferons (IFNs) are proteins made and released by...
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