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MDM2 Polyclonal Antibody

Cat no: ABP52917

MDM2 Polyclonal Antibody

MDM2 encodes a nuclear-localized E3 ubiquitin ligase. The MDM2 proto-oncogene can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

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SPECIFICATIONS

Catalog Number

ABP52917

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum

Gene Id

4193

Isotype

Rabbit IgG

Accession

Q00987

Clonality

Polyclonal

Concentration

1 mg/ml

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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