MDM2 Polyclonal Antibody

Cat no: ABP52917

Supplier: Abbkine Scientific Co.Ltd.

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MDM2 encodes a nuclear-localized E3 ubiquitin ligase. The MDM2 proto-oncogene can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Catalogue number:	ABP52917
Reactivities:	Human
Hosts:	Rabbit
Applications:	ELISA, Immunofluorescence, Immunohistochemistry - fixed, Western Blot
Size:	30micro l, 100micro l, 200micro l
Accession:	Q00987
Gene:	4193
Concentration:	1 mg/ml
Isotype:	Rabbit IgG
Clonality:	Polyclonal

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MDM2 Polyclonal Antibody

Cat no: ABP52917

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