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Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific...
Plk1 consists of 603 amino acids and is 66kDa. In addition to the N-terminus kinase domain, there are two conserved polo-box regions of 30 amino acids at the...
CNK is a member of the 'polo' family of serine/threonine kinases. Members of this family have been implicated in cell division and are important in...
PLOD1 encode a polypeptide of 709 amino acid residues and a signal peptide of 18 amino acids. The human coding sequence shows 72% identity to the chick...
PLOD2 is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate)...
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In...
PLUNC is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact...
PLXN1 alone did not bind semaphorin-3A (SEMA3A), but the NRP1/PLXN1 complex had a higher affinity for SEMA3A than did NRP1 alone. While SEMA3A binding to...
Tandem mass spectrometry of receptor peptides yielded partial amino acid sequences that allowed the identification of cDNA clones corresponding to the A39R...
May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular...
Probable transcription factor PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type...
Peripheral myelin protein 22, also known as PMP22, is a protein encoded by the PMP22 gene. Alternative splicing of this gene results in three transcript...
The deduced 486-amino acid protein contains a highly conserved 180-amino acid N-terminal patatin domain with a glycine-rich region, an active serine...
PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be...
PODNL1, Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily. Studies of mice lacking specific members of the small leucine...
DNA polymerase beta maintains genome integrity by participating in base excision repair. Over expression of POLB mRNA has been correlated with a number of...
Serum paraoxonase/arylesterase 2 is a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long...
The POR gene provides instructions for making the enzyme cytochrome P450 oxidoreductase. This enzyme is required for the normal functioning of more than 50...
PORCN has 5 transcript variants that encode 5 protein isoforms with tissue-specific variability and expression (PORCA-PROCE). To investigate how...
POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a...
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