Human Cytochrome P450 2E1 (CYP2E1) ELISA Kit

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

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SPECIFICATIONS

Catalog Number

KTE62167

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

1571

Accession

P05181

Additional Info

Human Cytochrome P450 2E1 (CYP2E1) ELISA Kit has high sensitivity and excellent specificity for detection of Human CYP2E1. No significant cross-reactivity or interference between Human CYP2E1 and analogues was observed.