Human Cytokeratin 18 (CK-18) ELISA Kit

Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.\nHuman keratin 18 and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. Endo B and its coexpressed type II keratin, Endo A (the mouse equivalent of human keratin 8), appear to be the first IF proteins expressed during murine development.

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SPECIFICATIONS

Catalog Number

KTE61881

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

3875

Accession

P05783

Additional Info

Human Cytokeratin 18 (CK-18) ELISA Kit has high sensitivity and excellent specificity for detection of Human KRT18. No significant cross-reactivity or interference between Human KRT18 and analogues was observed.