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Fanconi anemia group L protein (FANCL) is an ubiquitin ligase that mediates ubiquitination of FANCD2, a key step in the DNA damage pathway. FANCL is required...
Fanconi anemia group A protein (FANCA) is a DNA repair protein that operates in a postreplication repair or a cell cycle checkpoint function. FANCA is...
BLM, a helicase protein from the RecQ subfamily,Porcinearticipates in DNA replication and repair with a magnesium-dependent ATP-dependent DNA-helicase...
MUTYH is involved in o, Xenopus/Amphibian,ydative DNA damage repair by initiating repair of A-o, Xenopus/Amphibian,oG to C-G by removing the inappropriately...
Merlin (NF2) acts as a membrane stabilizing protein and may inhibit PI3 kinase by binding to CENTG1. Defects in NF2 are the cause of neurofibromatosis 2 and...
CDKN2A acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This interaction inhibits CDKs binding...
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked...
TYRO10 (DDR2) is a tyrosine kinase receptor for fibrillar collagen that mediates fibroblast migration and proliferation. TYRO10 contributes to cutaneous...
SLUG is a transcriptional repressor involved in the generation and migration of neural crest cells. Defects in SLUG are the cause of neural tube defects and...
EphB2 is a receptor for members of the ephrin-B family and acts as a tumor suppressor. Defects in EphB2 are involved in the development of prostate cancer...
Dnmt3B is required for genome wide de novo methylation and is essential for development. Defects in Dnmt3B are a cause of immunodeficiency-centromeric...
FLIP (FLICE-like inhibitory protein) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in...
Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of...
Matri, Xenopus/Amphibian, metalloproteinase family members are involved in the breakdown of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, in...
Synta, Xenopus/Amphibian,ins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Synta, Xenopus/Amphibian,in,...
Carbo, Xenopus/Amphibian,ypeptidase B1 preferentially releases the C-terminal amino acids Arg and Lys.
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a...
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a...
CD4 antigen is found on a T-cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. CD4 is also present on 80% of thymocytes and at a...
GSK3b (Glycogen synthase kinase-3 beta) participates in the Wnt signaling pathway. GSK3b is implicated in the hormonal control of several regulatory proteins...
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