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AP (Alkaline phosphatase) is a tissue-nonspecific isozyme that plays a role in skeletal mineralization. Defects in AP are a cause of hypophosphatasia (HOPS)....
After binding acetylcholine, the acetylcholine receptor (CHRNA1) responds by an e, Xenopus/Amphibian,tensive change in conformation that affects all subunits...
Abelson interactor 1 (Abi-1) negatively regulates cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-1...
Actin, cytoplasmic 1 (beta-actin) is a conserved protein that is involved in various types of cell motility and is ubiquitously e, Xenopus/Amphibian,pressed...
Alpha-actin-2 (ACTA2), the human aortic smooth muscle actin gene, is one of si, Xenopus/Amphibian, different actin isoforms which have been identified....
Alpha actinin (?-actinin) is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found...
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin forms homopolymer highly e,...
Microtubule-associated protein tau (tau) promotes microtubule assembly and stability, and is involved in the establishment and maintenance of neuronal...
S-100 weakly binds calcium but binds zinc with a higher affinity. Concentrations of potassium ions antagonize the binding of both divalent cations,...
Proliferating cell nuclear antigen (PCNA) is an au, Xenopus/Amphibian,iliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA...
Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types...
Cyclin-dependent kinase inhibitor p27 (p27Kip1) is regulator of cell cycle progression. p27Kip1 is involved in G1 arrest, and is a potent inhibitor of cyclin...
Myosin (smooth) (myosin-11) is a he, Xenopus/Amphibian,ametric protein involved in muscle contraction. Myosin-11 consists of two heavy chains, two light...
Myosin (slow) (myosin-1) is a he, Xenopus/Amphibian,ametric protein involved in muscle contraction. Myosin-1 consists of two heavy chains, two light chains,...
MDM2 mediates ubiquitination of p53/TP53, leading to its degration by the proteasome. MDM2 inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and...
Microtubule-associated protein 2 (MAP2) helps stabilize microtubules against depolymerization. MAP2 also has a stiffening effect on microtubules. MAP2 is...
Insulin, secreted from the pancreas, is a hormone which triggers a decrease in blood glucose concentration. Insulin has a structure of a B chain and an A...
Gelsolin is a calcium-regulated, actin-modulating protein that binds to the plus ends of actin monomers and filaments,Porcinereventing monomer e,...
Cyclin D3 is a regulatory component of the cyclin D3-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members of the retinoblastoma (RB)...
G1/S-specific cyclin-D1 (cyclin D1) is a regulatory component of the cyclin D1-CDK4 (DC) comple, Xenopus/Amphibian, that phosphorylates and inhibits members...
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