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Products S-100 (DB 055)
S-100 is a low molecular weight protein expressed in glial cells, chondrocytes, macrophages, Langerhans cells, dendritic cells, adipocytes, keratinocytes and breast epithelial cells.
S-100 is involved in regulation of protein phosphorylation, calcium homeostasis, cell differentiation, and inflammatory response.
In clinical diagnostics, S-100 protein expression is used as a marker of certain tumors, melanomas, peripheral nerve sheath tumors, and clear cell sarcomas.
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