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BUY Veratridine

Cat no: V-110

BUY Veratridine

Veratridine. An Enhancer of Nav Channel ActivityпїЅand an Inducer of Transmitter Release. Veratridine is an alkaloid extracted from the Veratrum officinale plant, which is a potent modulator of voltage dependent Na\\+\\channels and hence, of transmitter release. Veratridine reduces the single channel conductance and increases the persistent opening probability of Nav1.4 channels expressed in a mammalian cell line. Veratridine affects differentially the TTX-sensitive and TTX-resistant components of Nav currents in rat DRG neurons. Although veratridine inhibits both components at the peak current, it is much more effective in increasing the persistent component (channel opening) of the TTX sensitive currents. Veratridine is widely used in different excitable preparations to induce Nav channel dependent transmitter release. Ion Channel Modulators; Voltage - Gated Na+ Channel Activators.

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SPECIFICATIONS

Catalog Number

V-110

Size

25 mg

Purity

>99%

Concentration

1-200 uM

Shipping Temp

Room Temperature

Molecular Weight

673.8 da

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