Tetrodotoxin (with citrate). Classic Blocker of Subset Nav�Channels.
Tetrodotoxin (TTX) is an established potent and selective blocker of some Nav�channels. Moreover, TTX sensitivity is used to define subclasses of Nav�channels.
It is widely used both to probe Nav�activity and to reduce or block excitability in neurophysiological preparations.
Ion Channel Modulators; Voltage - Gated Na+ Channel Blockers.