Supplier:
Alomone Labs Limited.Cat no: STT-250
BUY Tertiapin
A Peptide Blocker of Inward Rectifier (K\\ir\\) K\\+\\ Channels
Tertiapin is a 21 amino acid long toxin, originally isolated from Apis mellifera bee venom.
Native and synthetic Tertiapin block a range of inward rectifier K\\+\\ channels. (K\\ir\\), in particular ROMK1 (K\\ir\\1.1, IC50 = 2nM) and GIRK (K\\ir\\3 family, IC50 for the K\\ir\\3.1/3.4 heteromer is 8.6 nM) but with no effect on K\\ir\\2 family members.
In addition, it was shown to inhibit acetylcholine induced K\\+\\ currents in heart.
Alomone Labs is pleased to offer Tertiapin (#STT-250)пїЅa synthetic peptide purified to homogeneity.
Tertiapin is as active as Tertiapin-Q (#STT-170), a derivative of Tertiapin in which the oxidation-liable methionine is replaced by aпїЅglutamine residue.
Ion Channel Modulators; K+ Channel Blockers
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SPECIFICATIONS
Catalog Number
STT-250
Size
0.5 mg
Purity
>98%
Concentration
10-100 nM
Shipping Temp
Room Temperature
Molecular Weight
2455 da
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