Supplier:
Alomone Labs Limited.Cat no: R-400
BUY Resiniferatoxin
Resiniferatoxin is a potent and selective agonist of the TRPV1 (Vanilloid/Capsaicin receptor) channel. Application of sub-nanomolar concentrations of Resiniferatoxin irreversibly induces a sustained slow current and depolarization in DRG neurons. Treatment of rats with Resiniferatoxin, like treatment with capsaicin, causes hypothermia, neurogenic inflammation and pain. These responses were followed by a loss of thermoregulation, by desensiization to neurogenic inflammation and by chemical and thermal analgesia, with a cross-tolerance between Resiniferatoxin and capsaicin.
Ion Channel Modulators; TRP Channel Modulators.
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SPECIFICATIONS
Catalog Number
R-400
Size
5 x 0.5 mg
Purity
>95%
Concentration
20 nM - 1 uM.
Shipping Temp
Room Temperature
Molecular Weight
628.72 da
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