Supplier:
Alomone Labs Limited.Cat no: P-650
BUY Penitrem A
Penitrem A is widely used to probe KCa1.1 channels in smooth muscle preparations, where it induces prolongation of the depolarization plateau potential. Penitrem A is a selective blocker of KCa1.1 (high-conductance Ca2+-activated K+, BK) channels. It belongs to a set of tremorgenic indole alkaloids which are lipid soluble and also include Verruculogen (#V-500) and Paxilline (#P-450). Penitrem A (400 mg mycelium/kg) increased the spontaneous release of endogenous glutamate, GABA (gamma-aminobutyric acid), and aspartate by 213%, 455%, and 277%, respectively, from rat cerebrocortical synaptosomes.Ion Channel Modulators; K+ Channel Blockers.
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SPECIFICATIONS
Catalog Number
P-650
Size
5 x 0.65 mg
Purity
>98%
Concentration
10-100 nM.
Shipping Temp
Room Temperature
Molecular Weight
634.2 da
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