Supplier:
Alomone Labs Limited.Cat no: P-360
BUY PD 153035
D 153035 is a small molecule derivated from brominated anilinoquinazoline which inhibits tyrosine kinase activity of the EGFR by competition at the ATP binding site. PD 153035 is a highly potent inhibitor for auto and hetro tyrosine kinase activity of EGF receptor (ERB2) at sub nM concentrations and inhibits other purified tyrosine kinases only at micromolar or higher concentrations. PD 153053 abolished all growth effects mediated by the addition of exogenous EGF in a receptor number-dependent manner and shows a remarkable apoptotic and cytotoxic activity against several types of tumor cell lines that overexpress the EGF receptor in vitro andin vivo. Protein Kinase Inhibitors and Activators; EGF Receptor Tyrosine Kinase Inhibitors
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SPECIFICATIONS
Catalog Number
P-360
Size
1 mg
Purity
>99%
Concentration
10-500 nM
Shipping Temp
Room Temperature
Molecular Weight
360.21
SUPPLIER INFO
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