Supplier:
Alomone Labs Limited.Cat no: C-670
BUY omega-Conotoxin MVIIA
omega-Conotoxin MVIIA inhibits K+-induced H-GABA release in hippocampus in vivo. This effect was with high affinity (50% block, 200 nM).
The toxin was used to inhibit synaptic transmission in several peripheral preparations. The toxin binds with high affinity to rat neocortical membranes. It blocked cloned Cav2.2 channels transiently expressed in tsa-2019 and in Xenopus oocytes.
The FDA recently approved Prialt (synthetic omega-Conotoxin MVIIA) to treat severe chronic pain in patients who are intolerant of or refractory to other treatments such as systemic analgesics or morphine.
This is the first ion channel blocker to be marketed for pain.
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SPECIFICATIONS
Catalog Number
C-670
Size
5 x 0.1 mg
Purity
>99%
Concentration
100 nM - 2 micro M
Shipping Temp
Room Temperature
Molecular Weight
2639.2 da
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