Ochratoxin A. A Potent�Modulator�of�Ca2+�ATPase Pump.
Ochratoxin A is a natural metabolic alkaloid produce by�Aspergillus�ochraceus.
Ochratoxin A is a potent a toxin�which causes nephrosis in mammals. In the circulation, Ochratoxin A has�a�very�long�half-life in�all�species examined.�Although the kidney is the primary target�organ for Ochratoxin A activity, studies indicate�that Ochratoxin�A is also a liver toxin, immunosuppressant, potent teratogen, and carcinogen.�
Ochratoxin A increases activity of the endoplasmic reticulum ATP-dependent Ca2+�pump.
Cell Ca2+ Signaling; Intracellular Ca2+ Mobilizers
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