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BUY mu-Conotoxin PIIIA

Cat no: STC-400

BUY mu-Conotoxin PIIIA

mu-Conotoxin PIIIA. A Potent Blocker of Nav1.2, Nav1.4 and Nav1.7 Na\\+\\ Channels.
mu-Conotoxin PIIIA is a 22 amino acid peptidyl toxin isolated from the Conus purpurascens (Purple cone) venom and belongs to the conotoxin M superfamily.
It reversibly blocks mammalian skeletal muscle voltage-gated Na\\+\\ channels (Nav1.4, IC50 of 44 nM), Type II (Nav1.2) and PN1 (Nav1.7) neuronal voltage-gated Na\\+\\ channels (IC50 of 640 nM) by binding to site I domain of the channel.
In addition, it blocks irreversibly amphibian muscle Na\\+\\ channels.
Ion Channel Modulators; Voltage - Gated Na\\+\\ Channel Blockers

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SPECIFICATIONS

Catalog Number

STC-400

Size

0.5 mg

Purity

>98 %

Concentration

10 nM - 1 micro M

Shipping Temp

Room Temperature

Molecular Weight

2604 da

SUPPLIER INFO

Alomone Labs Limited.

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