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BUY Margatoxin

Cat no: RTM-325

BUY Margatoxin

Margatoxin. A Potent Blocker of Kv1.3 K+пїЅChannels.
Margatoxin was originally isolated from the scorpion Centruroides margaritatus. It is a specific blocker of Kv1.3 channels (IC50~30pM), but it also blocks Kv1.6 and a splice variant of the Drosophila Shaker channels with IC50 of 5 and 150 nM respectively. In Xenopus oocytes the toxin was less potent and inhibited expressed Kv1.3 channels with an apparent IC50 of ~1 nM.

Ion Channel Modulators; K+ Channel Blockers.

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SPECIFICATIONS

Catalog Number

RTM-325

Size

10 micro g

Purity

>99%

Concentration

50 pM - 50 nM.

Shipping Temp

Room Temperature

Molecular Weight

4179 da

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