Supplier:
Alomone Labs Limited.Cat no: N-260
BUY hNT-3
The neurotrophins ("neuro" means nerve and "trophe" means nutrient) are a family пїЅof soluble, basic growth factors which regulate neuronal development, maintenance, survival and death in the CNS and the PNS. Of all the neurotrophins, Neurotrophin-3 (NT-3) shows the highest expression levels during the perinatal development, with most prominent expression levels in the hippocampus, the neocortex and the cerebellum. Release of endogenous NT-3 was observed from cultures of embryonic hippocampus following high K+ induced depolarization or stimulation with activity dependent neurotrophic factor (ADNF).
The structural hallmark of all the neurotrophins is the characteristic arrangement of the disulfide bridges known as the cysteine knot, which has been found in other growth factors such as PDGF. The rat and human forms of NT-3 are 96% homologous.
NT-3 has been shown to strengthen synaptic connections to motoneurons in the neonatal rat, to serve as an anti-inflammatory factor to suppress microglial activation, to play a critical role in regulating T helper 1/T helper 2 cell balance and to modify potassium currents in isolated inner hair cells from guinea pig cochlea. The biological effects of NT-3 are mediated by two receptors: TrkC, which is specific for NT-3 and p75, which binds all the neurotrophins.
Neurotrophic Factors; Neurotrophins
Prices direct from Alomone Labs Limited.
Quick response times
Exclusive Absave savings/discounts
SPECIFICATIONS
Catalog Number
N-260
Size
10 micro g
Purity
>98%
Concentration
Not determined
Shipping Temp
Room Temperature
Molecular Weight
27.2 kDa
SUPPLIER INFO
Latest promotions
Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...
New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...
Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...
10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...
For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...
We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!
Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...
Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...
Top suppliers
Agrisera AB
11 products
Biotrend
Biosensis
969 products
ABBIOTEC
3011 products
SDIX
1 products
Spring Bioscience
2291 products
Cell Signaling Technology
4976 products
Rockland Immunochemicals, Inc.
7592 products
Boster Immunoleader
1533 products
OriGene Technologies Inc.
5281 products
Maine Biotechnology Services
227 products
BD (Becton, Dickinson and Company)
1 products
ABNOVA CORPORATION
Randox Life Sciences
1502 products
