Supplier:
Alomone Labs Limited.Cat no: F-700
BUY FS-2
FS-2 is a natural peptidyl toxin isolated from the Dendroaspis p. polylepsis black mamba venom, by a modification of the procedure of Schweitz et al and purified to homogenity. FS2 is an L-type Cav channel blocker. The toxin reduced (пїЅ)Bay K 8644-induced [Ca2+]in increase, in smooth muscle cells as determined by Ca2+ imaging with Fura-2. The IC50 for this effect was 23 nM. FS2 induced relaxation in pre-constricted rat aorta, pulmonary artery and trachea. In addition, it inhibited acetylcholine induced contractions in guinea pig ileum.
Ion Channel Modulators; Voltage - Gated Ca2+ Channel Blockers.
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SPECIFICATIONS
Catalog Number
F-700
Size
70 micro g
Purity
>98%
Concentration
100 nM - 2 micro M.
Shipping Temp
Room Temperature
Molecular Weight
7026 da
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