Supplier:
Alomone Labs Limited.Cat no: F-110
BUY Flunarizine dihydrochloride
L-type (Cav1), voltage-gated Ca2+ channels are plasma membrane protein complexes which allow the passage of Ca2+ ions into cells following depolarization of the membrane potential.
L-type channels are widely expressed in cardiac and smooth muscle in which they control contraction and therefore were recognized as a therapeutic target for cardiovascular diseases.
Flunarizine dihydrochloride is a diphenylmethylpiperazine L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat migraine. Flunarizine dihydrochloride inhibits L- and T-type Cav channels in guinea pig ventricular cells with similar potency and in a use dependent manner.
Ion Channel Modulators; Voltage - Gated Ca2+ Channel Blockers.
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SPECIFICATIONS
Catalog Number
F-110
Size
10 g
Purity
>99%
Concentration
1-200 uM
Shipping Temp
Room Temperature
Molecular Weight
477.4 da
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