Cytochalasin E. Protein Synthesis and Transport Inhibitor. Cytochalasins are a group of fungal toxin metabolites which bind to actin and alter its polymerization. Cytochalasins bind to the barbed end of actin filament and prevent both the association and dissociation of actin subunits, by inhibiting cell microtubule formation, cell division and cell migration.� Cytochalasin E induced a rapid and sustained elevation of intracellular free Ca2+ in B lymphocytes by increasing the extracellular Ca2+ influx. Cell Signaling Activators and Inhibitors; Protein Synthesis and Transport Inhibitors.