Chlorotoxin. An Inhibitor of Some Chloride Channels. Native Chlorotoxin (CTX) is a 36-amino acid peptide, originally isolated from the venom of the giant yellow Israeli scorpion Leiurus quinquestriatus hebraeus. Primary amino acid sequence shows considerable homology to a class of short insectotoxins.
Initially, CTX has been demonstrated as an irreversible inhibitor of small conductance Cl
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