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BUY (A)-Conotoxin PeIA

Cat no: STC-950

BUY (A)-Conotoxin PeIA

(A)-Conotoxin PeIA is a peptide toxin originally isolated from the Conus pergrandis (Grand cone) venom. This toxin belongs to the (A)-Conotoxin family which acts on postsynaptic membrane, by binding and inhibiting nicotinic acetylcholine receptors (nAChR).\n \nIt potently and reversibly blocks (A)9/(A)10 nAChR (IC50 = 6.9 nM) and (A)3/(B)2 (IC50 = 23 nM) and discriminates between rat (A)9/(A)10 and (A)7 nACh recetors. It also inhibits N-type Ca2+ channels (CaV2.2), (IC50 = 1.1 nM) via the activation of the GABA(B) G-protein coupled receptor in DRG neurons.

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SPECIFICATIONS

Catalog Number

STC-950

Size

0.1 mg

Purity

>98 %

Concentration

20-50 nM

Shipping Temp

Room Temperature

Molecular Weight

20-50 Da

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