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BUY 5'-Iodoresiniferatoxin

Cat no: I-800

BUY 5'-Iodoresiniferatoxin

5'-Iodoresiniferatoxin. AпїЅPotent and Partial Antagonist of the TRPV1.
5пїЅ-Iodoresiniferatoxin (5пїЅ-IRTX) is a potent and partial antagonist of the TRPV1 (Vanilloid/capsaicin receptor) channel. It is an iodinated form of the potent agonist Resiniferatoxin (#R-400). 5пїЅ-Iodoresiniferatoxin partially blocked capsaicin induced currents in Xenopus oocytes expressing TRPV1 channels (IC50=3.9 nM). 5пїЅ-Iodoresiniferatoxin abolished an inhibitory effect of capsaicin on Cav currents (probably mediated by TRPV1) in DRG neurons.
Ion Channel Modulators; TRP Channel Modulators

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SPECIFICATIONS

Catalog Number

I-800

Size

0.5 mg

Purity

>99%

Concentration

100 nM - 10 micro M.

Shipping Temp

Room Temperature

Molecular Weight

755.6 da

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