MKI67 encodes a nuclear protein(marker of proliferation Ki-67) that is associated with and may be necessary for cellular proliferation. Alternatively spliced...
Tyrosine-protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be...
Janus kinase 2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively...
Cyclin E1 encoded by CCNE1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance...
Cyclin D1 encoded by CCND1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance...
Cyclin B1 encoded by CCNB1 is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor...
Cyclin A1 encoded by CCNA1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance...
Cyclin-dependent kinase 4 encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S....
CDK2 encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. Cyclin dependent kinase 2 is the catalytic...
Cyclin dependent kinase 1 encoded by CDK1 is a member of the Ser/Thr protein kinase family. Cyclin dependent kinase 1 is a catalytic subunit of the highly...
VEGFA?vascular endothelial growth factor A) is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a...
TIMP1 belongs to the TIMP gene family.Metalloproteinase inhibitor 1 encoded by this gene family are natural inhibitors of the matrix metalloproteinases...
PDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells...
PDGFB ?platelet derived growth factor subunit B)encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular...
Secreted phosphoprotein 1 encoded by SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. Secreted phosphoprotein 1 is secreted...
TNF receptor superfamily member 11b encoded by TNFRSF11B is a member of the TNF-receptor superfamily. TNF receptor superfamily member 11b is an...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as...
MMP2 is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular...
LTF is a member of the transferrin family of genes and lactotransferrin is found in the secondary granules of neutrophils. lactotransferrin is a major...
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the...