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SIRT1 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin...
RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Runt-related transcription...
PGR ?progesterone receptor)encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone,...
PPARG encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X...
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase...
PPARD?peroxisome proliferator activated receptor delta) encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear...
The protein encoded by EIF2AK3?eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic...
Eukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2,...
RPS6KB1 encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. Ribosomal protein S6 kinase B1 responds to mTOR (mammalian target of...
RPS6KB1 ?ribosomal protein S6 kinase B1)encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR...
RPS6KB1 ?ribosomal protein S6 kinase B1)encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR...
EP300?E1A binding protein p300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone...
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed...
NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates...
NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NF-kappa-B inhibitor alpha interacts with REL...
NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NFKB inhibitor alpha interacts with REL dimers to...
The protein encoded by NFKBIB?NFKB inhibitor beta) belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it...
IRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and...
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by CBX3?chromobox 3) binds...
CBX5 ?chromobox 5)encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the...
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