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TTR Mouse Monoclonal Antibody(1D7)

Cat no: ABM40340

TTR Mouse Monoclonal Antibody(1D7)

TTR?transthyretin) encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in TTR have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

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SPECIFICATIONS

Catalog Number

ABM40340

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F, WB

Hosts

Mouse

Reactivities

Hum

Gene Id

7276

Isotype

Mouse IgG1

Accession

P02766

Clonality

Monoclonal

Concentration

1 mg/ml

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