?-SMA Polyclonal Antibody

Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic ?- and ?-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility. The ?-cardiac and ?-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle ?-actin and ?-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The ?-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells .