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PKC Polyclonal Antibody

Cat no: ABP52223

PKC Polyclonal Antibody

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. Protein kinase C alpha by PRKCA is one of the PKC family members. Protein kinase C alphahas been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes

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SPECIFICATIONS

Catalog Number

ABP52223

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

5578/5579/5580/5581/5582/5583/5588/5590

Isotype

Rabbit IgG

Accession

P17252/P05771/Q05655/Q02156/P05129/P24723/Q04759/Q05513

Clonality

Polyclonal

Concentration

1 mg/ml

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