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PERK Polyclonal Antibody

PERK Polyclonal Antibody

Cat no: ABP57048

Supplier: Abbkine Scientific Co.Ltd.
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The protein encoded by EIF2AK3?eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in EIF2AK3 are associated with Wolcott-Rallison syndrome.
Catalogue number: ABP57048
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry - fixed, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: Q9NZJ5
Gene: 9451
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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