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PDGFR? Mouse Monoclonal Antibody(7A3)

Cat no: ABM40334

PDGFR? Mouse Monoclonal Antibody(7A3)

PDGFRA?platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that PDGFRA plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

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SPECIFICATIONS

Catalog Number

ABM40334

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

5156

Isotype

Mouse IgG1

Accession

P16234

Clonality

Monoclonal

Concentration

1 mg/ml

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