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p27 Polyclonal Antibody

p27 Polyclonal Antibody

Cat no: ABP52104

Supplier: Abbkine Scientific Co.Ltd.
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CDKN1B encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. Cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of cyclin dependent kinase inhibitor 1B, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in CDKN1B are associated with multiple endocrine neoplasia type IV (MEN4).
Catalogue number: ABP52104
Reactivities: Human
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry - fixed, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: P46527
Gene: 1027
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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