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NBR1 Mouse Monoclonal Antibody(7C3)

Cat no: ABM40366

NBR1 Mouse Monoclonal Antibody(7C3)

The protein encoded by NBR1 ?NBR1, autophagy cargo receptor)was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. NBR1 is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of NBR1 results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

ABM40366

Size

30micro l, 100micro l, 200micro l

Applications

IF, IHC-F

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Gene Id

4077

Isotype

Mouse IgG1

Accession

Q14596

Clonality

Monoclonal

Concentration

1 mg/ml

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