Mouse Transmembrane anterior posterior transformation protein 1 homolog (TAPT1) ELISA Kit

TAPT1 encodes a highly conserved protein that localizes to the centrosome and/or ciliary basal body. Mutations in TAPT1 disrupt Golgi morphology and trafficking and normal primary cilium formation and these mutations are congenitally manifested by severe undermineralization of the intra-uterine skeleton. A mutation in the mouse ortholog of TAPT1 results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. In mouse, TAPT1 is thought to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development.

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SPECIFICATIONS

Catalog Number

KTE70344

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

231225

Accession

Q4VBD2

Additional Info

Mouse Transmembrane anterior posterior transformation protein 1 homolog (TAPT1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TAPT1. No significant cross-reactivity or interference between Mouse TAPT1 and analogues was observed.