Mouse Toll-like receptor 5 (TLR-5) ELISA Kit

Toll-like receptor 5is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production.

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SPECIFICATIONS

Catalog Number

KTE70209

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

53791

Accession

Q9JLF7

Additional Info

Mouse Toll-like receptor 5 (TLR-5) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TLR5. No significant cross-reactivity or interference between Mouse TLR5 and analogues was observed.