Mouse TIMELESS-interacting protein (TIPIN) ELISA Kit

TIPIN associated with the components of the replicative helicase in human cell lines and protected cells against genotoxic agents. TIPIN was required for efficient cell cycle arrest in response to DNA damage, and depletion of TIPIN rendered cells sensitive to ionizing radiation as well as replication stress.It shares 72% amino acid identity with mouse Tipin, with the greatest divergence in the C termini. coexpression of Tim and Tipin in early embryonic and extraembryonic tissues, although Tipin was more widely expressed. After embryonic day 14.5, both Tim and Tipin were abundantly expressed in thymus, liver, gastrointestinal tract, and ventricular zone of brain, and Tipin was also expressed in lung. In adult mouse brain, Tipin was expressed in thalamic and cortical regions, with lower expression in suprachiasmatic nuclei.

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SPECIFICATIONS

Catalog Number

KTE70222

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

66131

Accession

Q91WA1

Additional Info

Mouse TIMELESS-interacting protein (TIPIN) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TIPIN. No significant cross-reactivity or interference between Mouse TIPIN and analogues was observed.