Mouse Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) ELISA Kit

PRDX3 encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

KTE70694

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

11757

Accession

P20108

Additional Info

Mouse Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PRDX3. No significant cross-reactivity or interference between Mouse PRDX3 and analogues was observed.