Mouse Tapasin (TAPBP) ELISA Kit

TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. TAPBP lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

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SPECIFICATIONS

Catalog Number

KTE70342

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

21356

Accession

Q9R233

Additional Info

Mouse Tapasin (TAPBP) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TAPBP. No significant cross-reactivity or interference between Mouse TAPBP and analogues was observed.