Mouse Talin-2 (TLN2) ELISA Kit

TLN2 encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.\nThe deduced 2,532-amino acid protein contains a FERM domain. In TLN1, the FERM domain binds the cytodomains of beta-1 and beta-3 integrins, as well as to F-actin and other proteins. TLN2 shares 74% identity with TLN1, and the N- and C-terminal regions of TLN2 are highly conserved across species.

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SPECIFICATIONS

Catalog Number

KTE70213

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

70549

Accession

Q71LX4

Additional Info

Mouse Talin-2 (TLN2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TLN2. No significant cross-reactivity or interference between Mouse TLN2 and analogues was observed.