Mouse Striatin-3 (STRN3) ELISA Kit

Anovel nuclear protein mainly expressed in S and G2 phase cells was characterized using autoantibodies from a cancer patient. cDNA clones were isolated by immunoscreening, and sequence analysis revealed that the cDNA clones encoded a 713-amino acid residue polypeptide which is provisionally named SG2NA. In the carboxyl terminal half of SG2NA, there are 6 copies of WD-40 motifs characteristic of a large family of proteins of which the prototype is beta-transducin/enhancer of split (TLE). In addition, there are nuclear localization sequence and phosphorylation sites related to the TLE proteins. Autoantibodies occurring spontaneously in certain cancer patients have been useful reagents for identifying cellular proteins and this is the first report of a novel WD-40 protein which is the target of an autoimmune response.

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SPECIFICATIONS

Catalog Number

KTE70273

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

94186

Accession

Q9ERG2

Additional Info

Mouse Striatin-3 (STRN3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse STRN3. No significant cross-reactivity or interference between Mouse STRN3 and analogues was observed.